A high-profile sex offender has gone missing from an Edison motel room where he lived, according to the chairman of the state Parole Board.

Paul Timmendequas, who was convicted of sex crimes against two young girls in 1999, did not return to his approved residence on Tuesday, according to James Plousis, the chairman of the Parole Board.

His last known address was room 102 of the Beauty Rest Motel on Route 1, according to Megan’s Law records. He was sentenced to a seven-year term at the Adult Diagnostic and Treatment Center for sexual offenders Avenel in 1999. He was released in February 2004, the Parole Board said.

Timmendequas, 51, is the brother of Jesse Timmendequas, who raped and murdered 7-year-old Megan Kanka in 1994. Megan’s Law, under which Paul Timmendequas must register his whereabouts, was named for her. Megan’s parents did not know that Jesse Timmendequas, a twice-convicted sex offender, was living across the street in Hamilton.

Jesse Timmendequas is serving a life term in prison.

The parole board’s Fugitive Task Force and local law enforcement are looking for Paul Timmendequas, Plousis said. Anyone with information on Timmendequas’ whereabouts should contact their police department.